The Influence of the Suprarenal Cortex on the Gonads of Rabbits. I. the Effects of Suprarenal Injury (by Removal or Freezing) on the Interstitial Cells 01~ the Ovary

I t is well known that hypertrophic changes occur in the interstitial cells of the ovary, and in the suprarenal cortex, in certain animals during pregnancy. Likewise, investigators are in general agreement that removal of the gonads causes hypertrophy of the suprarenal cortex. With these facts in mind, it occurred to us that conversely suprarenal injury might produce changes in the sex glands. We therefore studied the data of nearly 400 rabbits that had been subjected to various types of suprarenal injury. In the present communication the details of the observations on the changes which take place in the ovary following suprarenal injury are reported. Brief references to certain of these changes have already been made by one of us (1, 2) in other publications.